Scintigraphy using 99mTc-MIBI (sestamibi), a sensitive parameter of activity of multiple myeloma
Abstract:
Technetium-99m methoxyisobutylisonitrile (99mTc-MIBI) has been shown to be useful in identifying several types of tumors, such as breast, brain, thyroid gland, malignant lymphomas and multiple myeloma. In this study, 102 patients with multiple myeloma (MM) and 32 patients with monoclonal gammopathy of undetermined significance (MGUS) had been evaluated for correlation between 99mTc-MIBI and biochemical and hematological markers of activity of the disease. Significant statistical correlation was found between summary score (SS) of 99mTc-MIBI scintigrams and beta2-microglobulin (p