Issue 1-2/2025

Research progress on the regulation mechanism of DEPTOR expression and its role in tumorigenesis (1 — 15)

Jinni Jiang, Chengyu Zhao, Minglei Yang,  Guofang Zhao,  Jianfeng Shu

DOI: doi:10.4149/neo_2025_241203N504

Inhibition of enzymatic activity of HRD1 results in death of cells derived from glioblastoma multiforme, neuroblastoma, and normal astrocytes (16 — 24)

Jaroslava Guzikova, Monika Liskova, Lubos Hudak, Maria Brodnanova, Andrea Evinova, Jozef Hatok,  Peter Racay

DOI: doi:10.4149/neo_2025_241120N481

Nuclear factor I-C aggravates acute myelogenous leukemia by inhibiting SRY-box transcription factor 1 to activate autophagy (25 — 35)

Cong Luo, Zeyu Luo, Junjun Li, Feng Wen, Yixiong Cao, Qiong Liu,  Xingxing Long

DOI: doi:10.4149/neo_2025_240905N376

Triptonide inhibits the progression of oral squamous cell carcinoma by suppressing the TRIP13/c-Myc axis (36 — 47)

Hongbo Zhang, Zheng Wei, Shengwei Han,  Sufeng Zhao

DOI: doi:10.4149/neo_2025_240918N387

20(S)-ginsenoside Rg3 induced the necroptosis of prostate cancer cells via ROS overproduction (48 — 58)

Yanfei Peng, Yaping Guo, Shuwu Zhao, Hao Yan, Zheng Hao, Fang Zheng, Zhaiyi Zhang, Lin Miao,  Li-kang Sun,  Muriel Cuendet

DOI: doi:10.4149/neo_2025_240925N402

Elevated expression of HSF1 promotes the progression of colorectal cancer by activating CLDN3 transcription (67 — 79)

Yanxi Shao, Ting Ma, Dening Ma, Lue Hong, Min Lv, Shiqi Zhou, Zhibin Fang, Enyan Yu,  Xia Li,  Yuping Zhu

DOI: doi:10.4149/neo_2025_241031N442

Efficacy and prognostic factors of PD-1 inhibitors combined with apatinib in advanced diffuse gastric cancer (128 — 136)

Beibei Chen, Huichen Zhao, Huihui Hu, Jinxi Huang, Yingjun Liu, Huifang Lv, Weifeng Xu, Jianzheng Wang, Caiyun Nie, Jing Zhao, Yunduan He, Saiqi Wang, Yuhang Wang,  Xiaobing Chen

DOI: doi:10.4149/neo_2025_241021N429